The Period Circadian Protein 2 (Phospho-Ser662) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PER2. This antibody recognizes Human, and Mouse antigen. The Period Circadian Protein 2 (Phospho-Ser662) Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers')